| Morrissey MichaelPresident and CEO, Director · 321 transactions | — | 8.36M† | 11.22M | 30.0K | 2.73M |
| Caligan Partners LP +1 co-filerDirector, See Remarks, Director · 7 transactions | — | 1.57M† | 18.2K | 762.9K | 120.4K |
| Papadopoulos SteliosDirector · 77 transactions | — | 1.20M | 618.1K | 500.0K | 574.5K |
| Senner Christopher J.EVP and CFO · 98 transactions | — | 955.0K† | 2.57M | — | 790.2K |
| Haley Patrick J.EVP, Commercial · 167 transactions | — | 783.2K† | 1.91M | — | 1.20M |
| Scangos George ADirector · 1726 transactions | — | 738.3K†as of May 2020 | 584.1K | 25.0K | 1.36M |
| Schwab GiselaPres, Prod Dev & Med Aff & CMO · 141 transactions | — | 704.0K†as of Jul 2021 | 2.55M | 25.0K | 1.78M |
| Hessekiel JeffreyEVP & General Counsel · 133 transactions | — | 694.4K†as of May 2025 | 2.52M | — | 1.16M |
| Aftab DanaEVP, Research and Development · 48 transactions | — | 600.6K† | 1.13M | — | 499.3K |
| Peterson Amy C.EVP Prod Dev & Med Aff & CMO · 8 transactions | — | 538.2Kas of May 2025 | 573.7K | — | 72.8K |
| Willsey LanceDirector · 78 transactions | — | 464.4Kas of May 2022 | 372.0K | 456.2K | 441.3K |
| Lamb PeterEVP, Scientific Strategy & CSO · 168 transactions | — | 428.1K†as of Dec 2022 | 2.44M | — | 1.75M |
| Goodman Vicki LEVP, Prod Dev & Med Aff &CMO · 4 transactions | — | 307.7Kas of Apr 2023 | 332.6K | — | — |
| Wyszomierski Jack LDirector · 40 transactions | — | 284.4K | 527.4K | — | 243.0K |
| Cohen CharlesDirector · 45 transactions | — | 221.4Kas of Jul 2021 | 424.2K | — | 357.8K |
| Hefti BrendaSVP and General Counsel · 6 transactions | — | 208.3K† | 53.3K | — | 25.3K |
| Poste GeorgeDirector · 44 transactions | — | 127.2K | 550.0K | — | 422.8K |
| Freire Maria CDirector · 17 transactions | — | 109.2K | 190.5K | — | 81.3K |
| Karbe FrankEVP and CFO · 29 transactions | — | 106.7K†as of Feb 2014 | 31.3K | 34.0K | — |
| Marchesi Vincent TDirector · 53 transactions | — | 94.0Kas of May 2022 | 446.0K | 42.0K | 404.0K |
| Feldbaum Carl BDirector · 36 transactions | — | 58.7Kas of Feb 2023 | 358.7K | — | 333.3K |
| Garber Alan MDirector · 29 transactions | — | 54.9Kas of Mar 2024 | 370.9K | — | 335.2K |
| Wright JacquelineDirector · 3 transactions | — | 51.8Kas of Jun 2023 | 51.8K | — | — |
| Heyman Tomas J.Director · 5 transactions | — | 50.6K | 55.2K | — | 4.5K |
| Oliver BobDirector · 10 transactions | — | 29.5K | 79.4K | — | 48.9K |
| Smith JulieDirector · 19 transactions | — | 29.0K | 241.3K | — | 207.6K |
| Simonton Pamela AEVP, Exelixis · 47 transactions | — | 28.1K†as of Feb 2014 | 95.6K | — | 65.6K |
| Beckerle Mary CDirector · 12 transactions | — | 25.9K | 70.4K | — | 44.5K |
| Rivera Lupe MEVP, Operations · 29 transactions | — | 22.1K†as of Aug 2011 | 136.1K | — | 119.1K |
| Burke DeborahSVP & Chief Financial Officer · 6 transactions | — | 21.2K†as of Nov 2014 | 6.4K | — | — |
| Heller Frances KEVP, Business Development · 8 transactions | — | 17.3K†as of May 2011 | 15.6K | — | 13.1K |
| Eckhardt Sue GailDirector · 11 transactions | — | 16.1K | 60.2K | — | 44.1K |