Ionis Pharmaceuticals, Inc.
A biotech pioneer that designs medicines that target RNA—the body's genetic messengers—to treat diseases that were long considered "undruggable." Its medicines include SPINRAZA for spinal muscular atrophy and newer launches like WAINUA, TRYNGOLZA, and DAWNZERA, used mainly by patients with rare, neurological, and cardiometabolic conditions. Founded in 1989, it was originally named Isis Pharmaceuticals after the Egyptian goddess of healing, but renamed itself Ionis in 2015 to shake an unfortunate association with the militant group of the same name.
Granted 238.6K · Sold 250.9K
Granted 16.0K · Sold 16.0K
Granted 18.6K · Sold 19.5K
Granted 175.0K · Sold 225.2K
Granted 65.1K · Sold 85.1K
Granted 26.0K · Sold 31.8K
Granted 1.9K · Sold 973
Sold 10.6K
Granted 60.8K · Sold 60.8K
Sold 13.2K
Granted 78.3K · Sold 78.3K
Sold 5.0K
Granted 48.4K · Sold 53.8K
Granted 40.3K · Sold 54.9K
Granted 49.5K · Sold 42.2K
Granted 20.1K · Sold 26.3K
| Insider | Stake change | Holds now | Granted / vested | Bought | Sold |
|---|---|---|---|---|---|
| Monia Brett PChief Executive Officer, Director · 18 transactions | -3.7% | 245.6K | 238.6K | — | 250.9K |
| Berthelsen Spencer RDirector · 4 transactions | 0% | 156.1K | 16.0K | — | 16.0K |
| Baroldi JosephEVP, Chief Business Officer · 15 transactions | +3.6% | 98.9K | 18.6K | — | 19.5K |
| Hougen Elizabeth LEVP, Finance & CFO · 7 transactions | -37.8% | 82.7K | 175.0K | — | 225.2K |
| Bennett C FrankEVP, Chief Scientific Officer · 5 transactions | -19.9% | 80.6K | 65.1K | — | 85.1K |
| Schneider EugeneEVP, Chf Clinical Develop Ofcr · 3 transactions | +10.6% | 77.1K | 26.0K | — | 31.8K |
| Birchler BrianEVP, Corp and Development Ops · 2 transactions | +1.4% | 67.5K | 1.9K | — | 973 |
| Swayze EricEVP Research · 1 transaction | -14.1% | 64.3K | — | — | 10.6K |
| Kordasiewicz Holly B.EVP, Chief Development Officer · 6 transactions | +330.8% | 63.4K | 60.8K | — | 60.8K |
| O'Neil Patrick R.EVP CLO & General Counsel · 2 transactions | -15% | 61.5K | — | — | 13.2K |
| Loscalzo JosephDirector · 12 transactions | +3.4% | 54.1K | 78.3K | — | 78.3K |
| Parshall B LynneDirector · 2 transactions | -7.9% | 51.9K | — | — | 5.0K |
| Klein Joseph IIIDirector · 12 transactions | -14.5% | 31.6K | 48.4K | — | 53.8K |
| Diaz Allene M.Director · 6 transactions | +56.2% | 28.7K | 40.3K | — | 54.9K |
| Jenne KyleEVP, Chf GL Pdt Str Ofcr · 6 transactions | +44.7% | 23.7K | 49.5K | — | 42.2K |
| Devers Shannon L.EVP, Chief Human Resources Ofc · 9 transactions | -27.5% | 16.3K | 20.1K | — | 26.3K |
Select a row to see that insider’s individual transactions. Sum of the holdings confirmed in the 12 months before this insider's last filing. A Form 4 reports a holding per line — held directly, or through a named trust, partnership or foundation, and in each share class separately — never a person’s total. Lines not restated in that time are left out and shown apart: an active filer restates what they still hold, so a line they did not restate is more often an entity since renamed, whose shares a successor line reports too. An amber marker means some were left out.
Net open-market activity over the last 6 months: -974.7K shares. Grants, option exercises and tax withholding are excluded — they are compensation mechanics, not decisions to buy or sell.