Amylyx Pharmaceuticals, Inc.
A biopharmaceutical company that develops treatments for neurodegenerative diseases, founded in 2013 by two Brown University undergraduates, Joshua Cohen and Justin Klee. Their first drug, Relyvrio (sold as Albrioza in Canada), was approved in 2022 for ALS—the disease that gives the company its name, since "Amy" comes from "amyotrophic" and "lyx" nods to the breakdown of cells the drug targets. The company withdrew Relyvrio from the market in 2024 after a trial showed no clear benefit, though it kept the drug available free to patients already taking it.
| Holder | Schedule | % of class | Shares | Filed |
|---|---|---|---|---|
| Perceptive Advisors LLC | 13G/APassive | 7.5% | 8.28M | May 15, 2026 |
| Joseph Edelman | 13G/APassive | 7.5% | 8.28M | May 15, 2026 |
| Perceptive Life Sciences Master Fund, Ltd. | 13G/APassive | 7.5% | 8.28M | May 15, 2026 |
| The Vanguard Group | 13G/APassive | 0% | 0 | Mar 26, 2026 |
| TCG Crossover GP II, LLC | 13G/APassive | 5.7% | 6.24M | Feb 17, 2026 |
| TCG Crossover Fund II, L.P. | 13G/APassive | 5.7% | 6.24M | Feb 17, 2026 |
| Chen Yu | 13G/APassive | 5.7% | 6.24M | Feb 17, 2026 |
| Adage Capital Management, L.P. | 13G/APassive | 2.53% | 2.78M | Feb 12, 2026 |
| Robert Atchinson | 13G/APassive | 2.53% | 2.78M | Feb 12, 2026 |
| Phillip Gross | 13G/APassive | 2.53% | 2.78M | Feb 12, 2026 |