Anaptysbio, Inc.
A biotechnology company built around a platform that mimics somatic hypermutation — the natural process the human immune system uses to mature antibodies against threats. Founded in 2005 in San Diego by antibody engineers Tillman Gerngross and Nicholas Lydon, it developed drugs including dostarlimab (Jemperli), a cancer immunotherapy licensed to GSK. In 2026 it spun off its drug-development arm and now focuses on collecting royalties from its former programs. Its name nods to the antibody biology at its roots.
Bought 1.12M · Sold 668.2K
Bought 3.61M
Bought 50.0K
Sold 1.10M
Sold 37.0K
Bought 400.0K
Bought 400.0K
Bought 400.0K
Granted 1.07M · Sold 212.3K
Granted 16.5K · Bought 16.7K · Sold 33.0K
Granted 343.0K · Sold 279.4K
Granted 248.2K · Sold 59.2K
Granted 67.5K · Sold 23.5K
Granted 58.3K · Sold 20.6K
Granted 82.0K · Sold 58.5K
Granted 20.9K · Sold 11.0K
Granted 16.7K
Granted 124.6K · Sold 111.6K
Granted 11.9K
Granted 67.1K · Sold 56.1K
Granted 9.9K · Bought 3.6K · Sold 3.9K
Granted 9.9K · Sold 5.0K
Granted 37.0K · Sold 37.0K
| Insider | Stake change | Holds now | Granted / vested | Bought | Sold |
|---|---|---|---|---|---|
| Nodelman Oleg +1 co-filerDirector, 10% owner · 11 transactions | — | 7.88Mas of Jan 2025 | — | 1.12M | 668.2K |
| EcoR1 Capital, LLC10% owner · 4 transactions | — | 7.79Mas of Aug 2024 | — | 3.61M | — |
| Novo A/S10% owner · 6 transactions | — | 3.03Mas of Jan 2017 | — | 50.0K | — |
| Novo Holdings A/S10% owner · 9 transactions | — | 1.94Mas of Aug 2017 | — | — | 1.10M |
| Avalon Ventures VII L P +3 co-filers10% owner · 3 transactions | — | 1.67Mas of Jul 2017 | — | — | 37.0K |
| Topper James NDirector · 14 transactions | — | 980.5Kas of Nov 2020 | — | 400.0K | — |
| Every Nathan R +6 co-filers10% owner · 9 transactions | — | 973.6Kas of May 2018 | — | 400.0K | — |
| Every Nathan R +7 co-filers10% owner · 9 transactions | — | 973.6Kas of May 2018 | — | 400.0K | — |
| Faga DanielPresident, CEO, Director · 27 transactions | — | 510.6K | 1.07M | — | 212.3K |
| Lydon NicholasDirector · 10 transactions | — | 291.2Kas of Apr 2018 | 16.5K | 16.7K | 33.0K |
| Suria HamzaPresident, CEO, Director · 45 transactions | — | 93.3Kas of Dec 2021 | 343.0K | — | 279.4K |
| Londei MarcoChief Medical Officer · 17 transactions | — | 68.6Kas of Nov 2019 | 248.2K | — | 59.2K |
| Gallagher Carol GiltnerDirector · 1 transaction | — | 64.3Kas of Jan 2017 | — | — | — |
| Lizzul Paul F.Chief Medical Officer · 25 transactions | — | 42.1K | 67.5K | — | 23.5K |
| Schmid John P.Director · 10 transactions | — | 37.7K | 58.3K | — | 20.6K |
| Mulroy DennisCHIEF FINANCIAL OFFICER · 27 transactions | — | 21.9K | 82.0K | — | 58.5K |
| Marquet MagdaDirector · 5 transactions | — | 20.9K | 20.9K | — | 11.0K |
| Orwin John ADirector · 5 transactions | — | 16.7K | 16.7K | — | — |
| Loumeau Eric JCHIEF LEGAL OFFICER · 49 transactions | — | 12.8K | 124.6K | — | 111.6K |
| Jain RitaDirector · 2 transactions | — | 11.9Kas of Jun 2025 | 11.9K | — | — |
| Renton HollingsDirector · 16 transactions | — | 11.0K | 67.1K | — | 56.1K |
| Ware J. AnthonyDirector · 4 transactions | — | 9.6K | 9.9K | 3.6K | 3.9K |
| Fenton Dennis MDirector · 4 transactions | — | 5.0Kas of Jun 2025 | 9.9K | — | 5.0K |
| Piscitelli DominicChief Financial Officer · 7 transactions | — | 1.1Kas of Dec 2018 | 37.0K | — | 37.0K |
Select a row to see that insider’s individual transactions. Sum of the holdings confirmed in the 12 months before this insider's last filing. A Form 4 reports a holding per line — held directly, or through a named trust, partnership or foundation, and in each share class separately — never a person’s total. Lines not restated in that time are left out and shown apart: an active filer restates what they still hold, so a line they did not restate is more often an entity since renamed, whose shares a successor line reports too. An amber marker means some were left out.
Net open-market activity over all recorded history: +3.29M shares. Grants, option exercises and tax withholding are excluded — they are compensation mechanics, not decisions to buy or sell.