| Biotechnology Value Fund II LP +4 co-filersDirect Beneficial Owner · 99 transactions | — | 24.49M†as of Jan 2009 | — | 2.37M | — |
| Biotechnology Value Fund II LP +5 co-filersSee Explanation of Responses, 10% owner · 35 transactions | — | 6.18M†as of Feb 2012 | — | 103.4K | 905.1K |
| Gorman Kevin CharlesDirector · 125 transactions | — | 511.3K | 1.64M | — | 1.83M |
| Hawran Paul WExecutive VP and CFO · 20 transactions | — | 364.7K†as of May 2006 | — | — | 115.5K |
| Vale Wylie WDirector · 3 transactions | — | 231.9Kas of Mar 2006 | — | — | 10.0K |
| Bozigian Haig P.Chief Development Officer · 130 transactions | — | 152.7Kas of Nov 2020 | 613.1K | — | 815.0K |
| Gano KyleChief Executive Officer, Director · 108 transactions | — | 146.3K | 468.2K | — | 548.6K |
| Coughlin Timothy PChief Financial Officer · 56 transactions | — | 138.0Kas of Feb 2017 | 200.0K | — | 443.3K |
| Lyons Gary ADirector · 50 transactions | — | 122.1K | 298.3K | — | 252.0K |
| Valeur Jensen Margaret EEVP and General Counsel · 19 transactions | — | 118.3Kas of Feb 2011 | — | — | 61.8K |
| Grigoriadis Dimitri E.Chief Research Officer · 122 transactions | — | 82.3Kas of Oct 2021 | 557.9K | — | 851.5K |
| Benevich EricChief Commercial Officer · 85 transactions | — | 63.2K | 304.0K | — | 337.1K |
| Mollica Joseph ADirector · 10 transactions | — | 56.0Kas of Apr 2017 | 90.0K | — | — |
| OBrien Christopher FlintFormer Chief Medical Officer · 85 transactions | — | 55.9Kas of Feb 2018 | 383.2K | — | 705.2K |
| Lippoldt DarinChief Legal Officer · 127 transactions | — | 54.7K | 251.6K | — | 299.4K |
| Cooke JulieChief Human Resources Officer · 74 transactions | — | 45.1K | 115.0K | — | 155.4K |
| Rastetter William HDirector · 21 transactions | — | 43.7K | 159.2K | — | 115.5K |
| Nevinny Corinne HDirector · 15 transactions | — | 43.3Kas of May 2018 | 84.0K | — | 15.0K |
| Abernethy MattChief Financial Officer · 52 transactions | — | 42.8K | 88.4K | — | 122.3K |
| Lloyd-Smith MalcolmChief Integration Officer · 65 transactions | — | 42.3Kas of Feb 2023 | 143.9K | — | 200.9K |
| Pops Richard FDirector · 36 transactions | — | 37.8K | 179.4K | — | 115.8K |
| Roberts EiryChief Medical Officer · 56 transactions | — | 35.6Kas of Feb 2025 | 121.6K | — | 179.2K |
| Onyia JudeChief Scientific Officer · 39 transactions | — | 23.4K | 144.8K | — | 121.6K |
| Ranieri Richard JSr. VP, Human Resources · 16 transactions | — | 19.2Kas of Feb 2008 | — | — | 9.7K |
| Delaet IngridChief Regulatory Officer · 65 transactions | — | 16.2K | 57.1K | — | 39.4K |
| Mitchell W ThomasDirector · 18 transactions | — | 16.0Kas of Jun 2015 | 99.0K | 900 | 78.7K |
| Sherwin Stephen ADirector · 40 transactions | — | 15.9K | 204.4K | — | 151.5K |
| Morrow George JDirector · 9 transactions | — | 10.4K | 65.4K | — | 55.0K |
| Boyer David W.Chief Corp. Affairs Officer · 42 transactions | — | 7.8K | 23.8K | — | 53.7K |
| Mercier JohannaDirector · 3 transactions | — | 6.9K | 6.9K | — | — |
| Poon Christine ADirector · 2 transactions | — | 4.8K | 4.8K | — | — |
| Sharp ShaliniDirector · 4 transactions | — | 4.1K | 5.2K | — | 1.1K |
| Norwalk Leslie VDirector · 12 transactions | — | 2.8K | 23.2K | — | 20.4K |
| Keswani Sanjay ChandruChief Medical Officer · 2 transactions | — | 1.5K | 3.2K | — | — |