OREX

Orexigen Therapeutics Inc

A biopharmaceutical company based in La Jolla, California, that built its name on one drug: Contrave, an anti-obesity treatment combining two older medicines—naltrexone and bupropion—to curb hunger and cravings, which won FDA approval in 2014. It was founded in 2002 by Eckard Weber, who picked the name from "orexigenic," the term for appetite-stimulating signals—a playful irony for a company fighting obesity.