Pepgen Inc.
A clinical-stage biotech working to treat severe neuromuscular diseases, PepGen builds "oligonucleotide" medicines designed to fix faulty genetic instructions, using its EDO platform of cell-penetrating peptides to ferry drugs into muscle and other hard-to-reach tissues. Its lead candidate, PGN-EDODM1, targets myotonic dystrophy type 1 and has earned Orphan Drug and Fast Track designations. Founded in 2018, the company's name combines "Pep" for its peptide delivery technology and "Gen" for the genetic diseases it tackles.
Bought 1.08M
Bought 15.16M
Bought 416.7K
Granted 279.7K · Bought 53.2K · Sold 36.5K
Granted 103.3K · Sold 3.6K
Granted 69.7K · Bought 8.4K · Sold 1.9K
Granted 65.7K
Granted 51.3K · Sold 1.2K
Granted 16.4K · Sold 1.4K
Bought 4.2K
Granted 50.0K · Sold 50.0K
Granted 10.0K · Sold 10.0K
Granted 6.4K · Sold 6.4K
| Insider | Stake change | Holds now | Granted / vested | Bought | Sold |
|---|---|---|---|---|---|
| Oxford Science Enterprises plcFormer 10% Owner · 2 transactions | — | 4.96M | — | 1.08M | — |
| Kolchinsky Peter +4 co-filersDirector, 10% owner, Director · 7 transactions | — | 1.51M | — | 15.16M | — |
| Deerfield Management Company, L.P. (Series C) +5 co-filersReporting owner · 4 transactions | — | 953.6Kas of May 2022 | — | 416.7K | — |
| McArthur James GPresident and CEO, Director · 17 transactions | — | 296.5K | 279.7K | 53.2K | 36.5K |
| Donnelly NoelChief Financial Officer · 6 transactions | — | 111.6K | 103.3K | — | 3.6K |
| Streck PaulEVP, Head of R&D · 5 transactions | — | 76.2K | 69.7K | 8.4K | 1.9K |
| Vittiglio JosephChief Business & Legal Officer · 2 transactions | — | 65.7K | 65.7K | — | — |
| Kasraian KasraChief Technical Officer · 3 transactions | — | 50.1K | 51.3K | — | 1.2K |
| DeLena Mary BethGeneral Counsel · 3 transactions | — | 15.0Kas of Mar 2025 | 16.4K | — | 1.4K |
| Keating LaurieDirector · 1 transaction | — | 4.2Kas of May 2022 | — | 4.2K | — |
| Mellion Michelle LChief Medical Officer · 24 transactions | — | 0as of Jul 2024 | 50.0K | — | 50.0K |
| Svenstrup NielsSVP, Chem. Mfg & Controls · 2 transactions | — | 0as of May 2024 | 10.0K | — | 10.0K |
| Goyal JayaEVP, Res. & Preclin. Dev. · 8 transactions | — | 0as of Mar 2023 | 6.4K | — | 6.4K |
Select a row to see that insider’s individual transactions. Sum of the holdings confirmed in the 12 months before this insider's last filing. A Form 4 reports a holding per line — held directly, or through a named trust, partnership or foundation, and in each share class separately — never a person’s total. Lines not restated in that time are left out and shown apart: an active filer restates what they still hold, so a line they did not restate is more often an entity since renamed, whose shares a successor line reports too. An amber marker means some were left out.
Net open-market activity over all recorded history: +16.61M shares. Grants, option exercises and tax withholding are excluded — they are compensation mechanics, not decisions to buy or sell.