| Sanofi10% owner · 550 transactions | — | 21.10M†as of Jun 2020 | — | 7.45M | 23.60M |
| Sanofi-Aventis +1 co-filer10% owner · 1 transaction | — | 15.82Mas of Oct 2010 | — | 1.02M | — |
| Vagelos P RoyDirector · 364 transactions | — | 1.15M†as of Apr 2023 | 3.90M | — | 1.22M |
| Yancopoulos GeorgeBd. Co-Chair, President & CSO, Director · 387 transactions | — | 1.13M† | 4.90M | — | 1.06M |
| Schleifer Leonard SBd. Co-Chair, President & CEO, Director · 263 transactions | — | 716.6K† | 4.53M | — | 1.11M |
| Roberts WilliamVP Reg Dev & Med Safety · 139 transactions | — | 109.6K†as of Feb 2014 | 263.3K | — | 196.7K |
| Goldberg Murray ASVP Administration & Asst Secr · 384 transactions | — | 70.8K†as of Dec 2014 | 884.0K | — | 365.9K |
| Stahl NeilEVP Research and Development · 434 transactions | — | 59.3K†as of Dec 2024 | 1.62M | — | 615.2K |
| Murphy Andrew JEVP Research · 261 transactions | — | 52.2K† | 260.8K | — | 82.7K |
| Larosa Joseph JEVP General Counsel and Secret · 142 transactions | — | 45.6K† | 282.8K | — | 71.8K |
| Van Plew Daniel PEVP & General Mgr, Industrial · 265 transactions | — | 35.2K† | 850.6K | — | 326.7K |
| Powchik PeterSVP Clinical Development & Reg · 132 transactions | — | 34.8K†as of Dec 2016 | 443.2K | — | 184.3K |
| Shooter Eric MDirector · 137 transactions | — | 33.9K†as of Feb 2014 | 210.0K | — | 232.7K |
| Sing George LDirector · 194 transactions | — | 33.2K† | 259.5K | 20.0K | 311.9K |
| Terifay Robert JEVP Commercial · 107 transactions | — | 26.9K†as of Aug 2017 | 439.4K | — | 219.4K |
| Landry Robert EEVP Finance CFO · 443 transactions | — | 24.0K†as of Feb 2024 | 213.9K | — | 37.6K |
| Fenimore Christopher R.EVP Finance CFO · 151 transactions | — | 23.5K† | 112.4K | — | 34.4K |
| Kolinski StuartSVP General Counsel and Secret · 45 transactions | — | 20.0K†as of Jun 2010 | 39.2K | — | 23.4K |
| Ryan Arthur FDirector · 772 transactions | — | 17.6K | 236.5K | 10.0K | 157.0K |
| Aberman Michael SSVP Strategy Investor Relation · 116 transactions | — | 16.9K†as of Jun 2017 | 131.4K | — | 59.7K |
| McCourt MarionEVP Commercial · 107 transactions | — | 14.5K† | 67.9K | — | 41.9K |
| Brown Michael SDirector · 303 transactions | — | 12.9K† | 289.2K | — | 281.8K |
| McCorkle Douglas SVP Controller and Asst Treasur · 224 transactions | — | 11.0K†as of Dec 2015 | 174.4K | — | 134.7K |
| Baker Charles ADirector · 154 transactions | — | 9.0Kas of Sep 2017 | 165.0K | — | 156.0K |
| Gilman Alfred GDirector · 189 transactions | — | 8.9Kas of Aug 2015 | 210.0K | — | 173.4K |
| Rupp RandallSVP, Manufuring Operations · 43 transactions | — | 7.5Kas of Apr 2007 | 195.0K | — | 204.1K |
| Goldstein Joseph LDirector · 242 transactions | — | 6.7K | 259.2K | — | 266.7K |
| Pitofsky JasonSVP Controller · 22 transactions | — | 5.8K† | 4.5K | — | 3.0K |
| Poon Christine ADirector · 60 transactions | — | 5.2K | 104.5K | 655 | 99.7K |
| Zoghbi Huda YDirector · 51 transactions | — | 3.2K | 18.7K | — | 17.0K |
| Bassler Bonnie LDirector · 59 transactions | — | 3.2K | 31.5K | — | 29.8K |
| Tessier-Lavigne MarcDirector · 88 transactions | — | 2.4Kas of Jan 2023 | 103.4K | — | 100.6K |
| Coles N AnthonyDirector · 51 transactions | — | 1.7K | 33.4K | — | 31.7K |
| Ingram Robert AlexanderDirector · 3 transactions | — | 1.5Kas of May 2015 | 6.7K | — | 1.4K |
| Thompson Craig B.Director · 5 transactions | — | 775 | 775 | — | — |
| Guarini KathrynDirector · 4 transactions | — | 603 | 603 | — | — |
| Schenkein David PDirector · 4 transactions | — | 603 | 603 | — | — |