Siga Technologies, Inc.
A pharmaceutical company that makes antiviral drugs for serious infectious diseases and biothreats, best known for TPOXX (tecovirimat), the first drug approved in the U.S. to treat smallpox and stockpiled by governments against bioterror threats. Founded in 1995 by Steven Oliveira and based in New York City, it works with U.S. agencies like BARDA on medical countermeasures. Fun fact: since smallpox was eradicated, TPOXX won approval under the FDA's "Animal Rule," which allows a drug to be approved on animal studies when human trials aren't possible.