Sionna Therapeutics, Inc.
A clinical-stage biopharmaceutical company developing small-molecule drugs for cystic fibrosis, a genetic lung disease. Its lead candidates SION-719 and SION-451 target a genetic defect found in about nine in ten people with the condition, aiming to complement the standard therapy Trikafta. Founded in 2019 by two scientists building on decades of CFTR research, the company began life as Sling Therapeutics before renaming itself Sionna in 2021.
Sold 540.3K
Sold 250.0K
Sold 1.03M
Sold 1.03M
Sold 698.4K
Granted 150.0K · Sold 150.0K
Sold 9.6K
Granted 30.8K · Sold 30.8K
| Insider | Stake change | Holds now | Granted / vested | Bought | Sold |
|---|---|---|---|---|---|
| Kolchinsky Peter +5 co-filersDirector, 10% owner, Director · 44 transactions | — | 19.13M | — | — | 540.3K |
| Coulter James G +2 co-filers10% owner · 1 transaction | -3.7% | 6.49M | — | — | 250.0K |
| Orbimed Advisors LLC +1 co-filerDirector · 18 transactions | — | 5.34M | — | — | 1.03M |
| Thompson Peter A.Director · 18 transactions | — | 5.34M | — | — | 1.03M |
| Booth BruceDirector · 50 transactions | -15.9% | 3.06M | — | — | 698.4K |
| Cloonan MichaelPresident & CEO, Director · 18 transactions | +5.5% | 577.4K | 150.0K | — | 150.0K |
| Ridloff ElenaCFO & Head of Corp. Dev. · 2 transactions | -19.9% | 38.5K | — | — | 9.6K |
| Fitzpatrick JenniferChief Legal Officer · 6 transactions | — | 10.3K | 30.8K | — | 30.8K |
Select a row to see that insider’s individual transactions. Sum of the holdings confirmed in the 12 months before this insider's last filing. A Form 4 reports a holding per line — held directly, or through a named trust, partnership or foundation, and in each share class separately — never a person’s total. Lines not restated in that time are left out and shown apart: an active filer restates what they still hold, so a line they did not restate is more often an entity since renamed, whose shares a successor line reports too. An amber marker means some were left out.
Net open-market activity over the last year: -3.75M shares. Grants, option exercises and tax withholding are excluded — they are compensation mechanics, not decisions to buy or sell.