| Kakkis Emil DPresident & CEO, Director · 108 transactions | — | 4.85M† | 649.0K | 12.5K | 713.2K |
| FMR LLCSee Remark 1. · 4 transactions | — | 4.72M†as of Aug 2014 | — | 175.0K | — |
| Bonderman David +2 co-filersFormer 10% Owner (2)(3)(4)(5) · 2 transactions | — | 2.60Mas of Jul 2014 | — | — | 488.8K |
| Kassberg Thomas RichardCBO & EVP · 65 transactions | — | 265.2Kas of Mar 2025 | 276.7K | 1.5K | 139.4K |
| Huang Dennis KarlSee Remarks · 45 transactions | — | 147.8K | 175.5K | — | 9.5K |
| Aliski WilliamDirector · 34 transactions | — | 137.2K†as of Jun 2021 | 81.1K | 5.0K | 87.3K |
| Pinion John RichardSee Remarks · 49 transactions | — | 133.1K | 190.7K | — | 49.6K |
| Harris ErikEVP & Chief Commercial Officer · 40 transactions | — | 118.4K | 160.7K | — | 52.1K |
| Crombez EricEVP and Chief Medical Officer · 14 transactions | — | 111.2K | 102.2K | — | 18.8K |
| Horn HowardChief Financial Officer · 17 transactions | — | 105.7K | 156.2K | — | 50.5K |
| Sharp ShaliniEVP, Finance · 93 transactions | — | 97.8Kas of Oct 2020 | 236.8K | 4.5K | 222.6K |
| Parschauer Karah HerdmanEVP and Chief Legal Officer · 72 transactions | — | 94.5K | 244.6K | — | 147.4K |
| Huizenga Theodore AlanSVP, Chief Accounting Officer · 93 transactions | — | 68.9K | 109.9K | — | 37.8K |
| Dier MardiCFO & Executive Vice President · 10 transactions | — | 66.7Kas of Oct 2022 | 79.5K | — | 12.8K |
| Bedrosian Camille LEVP and Chief Medical Officer · 30 transactions | — | 46.7Kas of Mar 2023 | 102.6K | — | 51.1K |
| Narachi MichaelDirector · 11 transactions | — | 40.4K | 40.4K | — | — |
| Welch Daniel GDirector · 11 transactions | — | 40.4K | 40.4K | — | — |
| Dunsire DeborahDirector · 10 transactions | — | 38.6K | 38.6K | — | — |
| Fust Matthew KDirector · 25 transactions | — | 33.7K | 65.4K | 5.0K | 33.4K |
| Ray AmritDirector · 6 transactions | — | 31.1K | 31.1K | — | — |
| Suliman ShehnaazDirector · 9 transactions | — | 28.0K | 33.7K | — | 5.7K |
| Dallas Jayson Donald AlexanderEVP & Chief Commercial Officer · 10 transactions | — | 23.8Kas of Jun 2018 | 25.8K | — | — |
| Sanders Corazon (Corsee) D.Director · 12 transactions | — | 21.1K | 29.9K | — | 8.8K |
| Hogenhuis WladimirChief Operating Officer · 3 transactions | — | 18.7Kas of Oct 2019 | 20.0K | — | — |
| Ekman LarsDirector · 7 transactions | — | 17.7Kas of Jun 2022 | 17.7K | — | — |
| Agarwal SunilChief Medical Officer · 36 transactions | — | 9.1Kas of Aug 2016 | 43.9K | — | 23.7K |
| Siegall Clay BDirector · 11 transactions | — | 4.1Kas of Aug 2020 | 37.3K | — | 34.8K |