| Kolchinsky Peter +3 co-filers10% owner · 2 transactions | — | 34.75M†as of Jun 2020 | — | — | 2.46M |
| Ridgeback Capital Investments L.P. +2 co-filers10% owner · 1 transaction | — | 10.07Mas of Mar 2020 | — | — | — |
| Evnin Luke +9 co-filersFormer 10% stockholder · 2 transactions | — | 3.97M†as of Feb 2012 | — | 100.0K | — |
| Longwood Fund, L.P.10% owner · 6 transactions | — | 3.79M†as of Jan 2014 | 600.0K | — | — |
| Westphal Christoph HExecutive Chairman, Director · 77 transactions | — | 2.97M†as of Jul 2015 | 869.9K | 1.24M | — |
| CHP III LP10% owner · 6 transactions | — | 2.33Mas of Jun 2013 | — | 95.0K | — |
| Clarke John KDirector · 10 transactions | — | 2.33Mas of Jun 2013 | — | 345.0K | — |
| CHP III LP +1 co-filer10% owner · 2 transactions | — | 2.23Mas of Jan 2012 | — | 250.0K | — |
| BVP VII Special Opportunity Fund LP +5 co-filersDirector, 10% owner · 4 transactions | — | 1.96Mas of Feb 2012 | — | 100.0K | — |
| Gadicke AnsbertDirector · 5 transactions | — | 1.94M†as of Feb 2012 | — | 100.0K | — |
| Aldrich RichardDirector · 25 transactions | — | 1.25M†as of May 2014 | 600.0K | 21.0K | — |
| Paterson DanPresident and CEO, Director · 81 transactions | — | 591.2K | 1.44M | 9.0K | 232.7K |
| Forrester RobertPresident and CEO, Director · 23 transactions | — | 226.2K†as of Oct 2018 | 142.9K | 18.5K | — |
| Barberich Timothy JDirector · 7 transactions | — | 218.0Kas of Dec 2020 | — | 218.0K | — |
| Neumann FrankChief Medical Officer · 1 transaction | — | 150.0Kas of Jan 2021 | 150.0K | — | — |
| Stuglik Brian MDirector · 45 transactions | — | 137.1K | 1.65M | 1.0K | 127.9K |
| Calkins DanielChief Financial Officer · 40 transactions | — | 117.2K | 133.2K | — | 27.2K |
| Bailey Michael PDirector · 1 transaction | — | 108.0K | 108.0K | — | — |
| Pachter JonathanVP, Head of Research · 6 transactions | — | 62.2Kas of Aug 2014 | 85.7K | 1.0K | — |
| Johnson JohnDirector · 3 transactions | — | 52.7K | 52.7K | — | — |
| Kapur AnilDirector · 3 transactions | — | 52.7K | 52.7K | — | — |
| Robertson MichelleDirector · 3 transactions | — | 52.7K | 52.7K | — | — |
| Rowinsky Eric KDirector · 4 transactions | — | 52.7K | 52.7K | 2.0K | — |
| Tollefson Karin AnnaDirector · 3 transactions | — | 52.7K | 52.7K | — | — |
| Ros MatthewChief Operating Officer · 1 transaction | — | 50.0Kas of Apr 2025 | 50.0K | — | — |
| Termeer Henri ADirector · 4 transactions | — | 46.2K†as of Dec 2014 | — | 46.2K | — |
| Bunn Paul A.Director · 6 transactions | — | 44.3K | 58.9K | — | 14.6K |
| Gagnon Robert E.Director · 40 transactions | — | 41.7K | 785.8K | — | 87.4K |
| Phanstiel S. LouiseDirector · 4 transactions | — | 26.5Kas of Dec 2014 | — | 26.5K | — |
| Lobacki Joseph MExecutive VP & CCO · 2 transactions | — | 10.7Kas of Sep 2018 | — | 10.7K | — |
| Kauffman MichaelDirector · 8 transactions | — | 8.7K | 20.7K | 7.0K | 11.6K |
| Bloom Steven H.Chief Strategy Officer · 1 transaction | — | 3.5Kas of Jun 2018 | — | 3.0K | — |
| Friedman Paul ADirector · 1 transaction | — | 3.0Kas of Dec 2014 | — | 3.0K | — |
| Green John BChief Financial Officer · 4 transactions | — | 2.5Kas of Jun 2015 | — | 2.5K | — |
| Lawton Alison FrancesDirector · 1 transaction | — | 2.5Kas of Nov 2014 | — | 2.5K | — |
| Sherwin Stephen ADirector · 1 transaction | — | 2.5Kas of Dec 2014 | — | 2.5K | — |
| Singh MonicaGeneral Counsel · 2 transactions | — | 2.0Kas of Jun 2015 | — | 2.0K | — |
| Horobin JoannaChief Medical Officer · 1 transaction | — | 750as of Dec 2014 | — | 750 | — |
| Kraus StephenDirector · 4 transactions | — | 0†as of Feb 2012 | — | — | — |