| Blutt Mitchell J MD +2 co-filers10% owner · 1 transaction | — | 4.59M†as of Mar 2016 | — | — | 120.0K |
| Dart Kenneth Bryan +2 co-filers10% owner · 1 transaction | — | 787.5Kas of Jul 2014 | — | — | — |
| Armstrong R Douglas PHDDirector · 3 transactions | — | 577.1Kas of Jul 2006 | 3.3K | 11.0K | — |
| Colangelo DominickPresident and CEO, Director · 156 transactions | — | 321.3K | 1.31M | 20.0K | 934.8K |
| Michel Gerard JCFO and VP, Corp. Development · 49 transactions | — | 240.6Kas of Apr 2020 | 392.4K | 20.0K | 174.0K |
| Sims Nelson MDirector · 4 transactions | — | 235.0K†as of Oct 2008 | 225.0K | 10.0K | — |
| Mayleben Timothy MPresident and CEO, Director · 9 transactions | — | 133.0Kas of Aug 2011 | — | 132.1K | — |
| Hopper Jonathan MarkChief Medical Officer · 93 transactions | — | 75.8K | 245.4K | — | 159.4K |
| Rubino Alan LDirector · 16 transactions | — | 64.2K | 63.3K | 890 | — |
| Orlando DanielChief Operating Officer · 27 transactions | — | 60.0Kas of Mar 2019 | 76.1K | 9.8K | 34.2K |
| Cresswell Ronald MDirector · 2 transactions | — | 40.0Kas of Aug 2011 | — | 40.0K | — |
| Hock Janet MaryVP Global Research & CSO · 4 transactions | — | 37.1Kas of May 2006 | 46.9K | — | 37.1K |
| Hagen HeidiDirector · 16 transactions | — | 35.0K | 59.0K | — | 24.0K |
| Zerbe Robert L MDDirector · 35 transactions | — | 33.0K | 85.8K | — | 48.5K |
| Brennan Gerald JRVP Admin. and Finance, CFO · 2 transactions | — | 30.0Kas of Nov 2007 | — | 30.0K | — |
| Sudovar StephenDirector · 2 transactions | — | 26.9Kas of Sep 2007 | — | 20.0K | — |
| Wotton Paul KDirector · 29 transactions | — | 26.3K | 114.5K | — | 95.7K |
| McLaughlin Kevin FDirector · 29 transactions | — | 18.3K | 74.3K | — | 56.0K |
| Halpin MichaelChief Operating Officer · 81 transactions | — | 16.2K | 250.4K | — | 184.4K |
| Mara Joseph Anthony JrChief Financial Officer · 46 transactions | — | 16.0K | 56.0K | — | 24.0K |
| Wright LisaDirector · 8 transactions | — | 15.9K | 15.9K | — | — |
| Dunbar George W JrDirector · 3 transactions | — | 12.8Kas of Mar 2010 | — | 39.0K | — |
| Gilman Steven CDirector · 28 transactions | — | 11.0Kas of Oct 2024 | 81.9K | — | 70.9K |
| Mahoney KarenChief Human Resources Officer · 2 transactions | — | 2.6Kas of Jul 2025 | 2.6K | — | — |
| Flynn Sean C.Chief Legal Officer · 65 transactions | — | 1.6K | 133.1K | — | 116.6K |
| Siegal JonathanPrincipal Accounting Officer · 47 transactions | — | 886 | 25.9K | — | 19.5K |
| Durbin ScottCFO · 7 transactions | — | 850†as of Jan 2012 | — | 40.9K | 40.0K |