Crispr Therapeutics AG
A biotech company that turns the CRISPR gene-editing discovery into medicines for serious inherited diseases. Its first approved therapy, Casgevy, treats sickle cell disease and beta-thalassemia by editing a patient's own blood stem cells. Co-founded in 2013 by Emmanuelle Charpentier — one of the scientists who shared the Nobel Prize for discovering CRISPR — along with Rodger Novak and Shaun Foy, the company takes its name directly from the gene-editing system it commercializes.
Granted 1.05M · Bought 989.8K
Granted 460.5K · Sold 456.4K
Granted 76.1K · Sold 38.3K
Granted 14.2K · Sold 6.8K
Bought 20.0K
Granted 28.1K · Bought 1.5K · Sold 10.9K
Granted 114.0K · Sold 97.7K
Bought 7.0K
| Insider | Stake change | Holds now | Granted / vested | Bought | Sold |
|---|---|---|---|---|---|
| George SimeonDirector · 6 transactions | — | 2.04Mas of Jul 2025 | 1.05M | 989.8K | — |
| Kulkarni SamarthChief Executive Officer, Director · 57 transactions | — | 341.1K | 460.5K | — | 456.4K |
| Kasinger James R.General Counsel and Secretary · 28 transactions | +75.9% | 94.3K | 76.1K | — | 38.3K |
| Bruno JulianneChief Operating Officer · 10 transactions | — | 27.8Kas of Mar 2025 | 14.2K | — | 6.8K |
| Treco Douglas ADirector · 1 transaction | +1000% | 22.0Kas of Aug 2025 | — | 20.0K | — |
| Patel NaimishChief Medical Officer · 7 transactions | — | 19.4K | 28.1K | 1.5K | 10.9K |
| Prasad RajuChief Financial Officer · 23 transactions | — | 15.6K | 114.0K | — | 97.7K |
| Greene JohnDirector · 1 transaction | — | 7.0Kas of Feb 2025 | — | 7.0K | — |
Select a row to see that insider’s individual transactions. Sum of the holdings confirmed in the 12 months before this insider's last filing. A Form 4 reports a holding per line — held directly, or through a named trust, partnership or foundation, and in each share class separately — never a person’s total. Lines not restated in that time are left out and shown apart: an active filer restates what they still hold, so a line they did not restate is more often an entity since renamed, whose shares a successor line reports too. An amber marker means some were left out.
Net open-market activity over the last 3 years: +408.3K shares. Grants, option exercises and tax withholding are excluded — they are compensation mechanics, not decisions to buy or sell.