| Foley ToddDirector · 50 transactions | — | 66.69M†as of Mar 2021 | — | 478.5K | 2.17M |
| Kolchinsky Peter +3 co-filersFormer 10% Owner · 12 transactions | — | 9.70M†as of Dec 2020 | — | — | 520.4K |
| Evnin Luke +5 co-filers10% owner · 2 transactions | — | 5.32M†as of Oct 2017 | — | 100.0K | — |
| Barrett M James10% owner · 3 transactions | — | 4.91Mas of Oct 2017 | — | 550.0K | — |
| Barris Peter J10% owner · 3 transactions | — | 4.91Mas of Oct 2017 | — | 550.0K | — |
| Baskett Forest10% owner · 3 transactions | — | 4.91Mas of Oct 2017 | — | 550.0K | — |
| Mott David M10% owner · 3 transactions | — | 4.91Mas of Oct 2017 | — | 550.0K | — |
| NEA Partners 13, Limited Partnership +2 co-filers10% owner · 3 transactions | — | 4.91Mas of Oct 2017 | — | 550.0K | — |
| Sandell Scott D10% owner · 3 transactions | — | 4.91Mas of Oct 2017 | — | 550.0K | — |
| Viswanathan Ravi10% owner · 3 transactions | — | 4.36Mas of Oct 2017 | — | 550.0K | — |
| Isaly Samuel D +2 co-filers10% owner · 2 transactions | — | 2.90Mas of Oct 2017 | — | 355.0K | — |
| Orbimed Advisors LLC +1 co-filerReporting owner · 4 transactions | — | 2.75Mas of May 2018 | — | — | 151.2K |
| Baker Bros. Advisors LP +3 co-filersFormer 10% owner · 4 transactions | — | 2.05M†as of Oct 2017 | — | 885.0K | — |
| Ipsen, S.A.10% owner · 3 transactions | — | 1.65M†as of Oct 2017 | — | 20.0K | — |
| Kerins Patrick J10% owner · 3 transactions | — | 1.43Mas of Oct 2017 | — | 550.0K | — |
| Pfizer Inc10% owner · 3 transactions | — | 1.39Mas of Oct 2017 | — | 40.0K | — |
| Deerfield Management Co +5 co-filersReporting owner · 4 transactions | — | 759.5K†as of Oct 2017 | — | 355.0K | — |
| Gottesdiener Keith MichaelCEO & President, Director · 21 transactions | — | 558.3Kas of Mar 2020 | 53.8K | — | 82.5K |
| Hadley Harbor Master Investors (Cayman) L.P.10% owner · 1 transaction | — | 545.3Kas of Oct 2017 | — | — | — |
| Meeker David PPresident and CEO, Director · 16 transactions | — | 270.5K | 260.8K | 35.0K | 107.6K |
| Smith Hunter CChief Financial Officer · 83 transactions | — | 119.6K | 329.5K | — | 200.7K |
| Levin Mark J +5 co-filers10% owner · 2 transactions | — | 99.1Kas of Sep 2018 | — | — | — |
| Mazabraud YannEVP, Head of International · 24 transactions | — | 66.0K | 184.3K | — | 121.7K |
| Desikan NithyaChief Commercial Officer · 7 transactions | — | 43.6Kas of Aug 2020 | 103.8K | — | 60.2K |
| Van der Ploeg Leonardus H.T.Chief Scientific Officer · 21 transactions | — | 42.3Kas of May 2019 | 75.0K | — | 95.0K |
| Cramer Pamela J.Chief Human Resources Officer · 61 transactions | — | 29.4K | 213.7K | — | 184.5K |
| Lee Jennifer KaydenEVP, Head of North America · 53 transactions | — | 28.5K | 183.1K | — | 160.5K |
| Shulman JosephChief Technical Officer · 64 transactions | — | 25.5K | 269.3K | — | 177.6K |
| Mathers Edward TDirector · 5 transactions | — | 21.2K† | 7.0K | — | — |
| Good Jennifer LDirector · 17 transactions | — | 11.7K | 95.2K | — | 83.5K |
| Tetrault LYNN A.Director · 17 transactions | — | 11.7K | 83.7K | — | 72.0K |
| McGirr David W JDirector · 6 transactions | — | 11.7K | 77.1K | — | 65.4K |
| Arbuckle Stuart ADirector · 3 transactions | — | 11.7K | 11.7K | — | — |
| Jean ChristopheDirector · 3 transactions | — | 11.7K | 11.7K | — | — |
| Roberts William T.Chief Accounting Officer · 5 transactions | — | 7.9Kas of Mar 2023 | 5.0K | — | 2.9K |
| Garfield AlastairChief Scientific Officer · 5 transactions | — | 7.8K | 11.1K | — | 1.3K |
| Bedrosian Camille LDirector · 2 transactions | — | 7.0Kas of Jun 2025 | 7.0K | — | — |
| Chien JenniferEVP, Head of North America · 5 transactions | — | 4.9Kas of Feb 2023 | 4.1K | — | 2.6K |
| German Christopher PaulCorporate Controller & CAO · 25 transactions | — | 1.9K | 20.3K | — | 19.0K |
| Exter NeilDirector · 1 transaction | — | 0†as of Oct 2017 | — | — | — |