| Krieg Harry JDirector · 6 transactions | — | 373.5K†as of Nov 2007 | 600 | — | — |
| Signorelli Andrew JDirector · 16 transactions | — | 240.7K†as of Apr 2013 | 4.1K | — | 152.2K |
| Brunngraber Eric HExecutive Chairman, Director · 170 transactions | — | 171.8K | 360.3K | — | 51.7K |
| Bodine Robert JDirector · 2 transactions | — | 165.2K†as of May 2006 | 600 | — | 732 |
| Cass Information Systems IncExecutive Chairman, Director · 4 transactions | — | 147.8Kas of Jan 2024 | 24.1K | — | — |
| Collett Lawrence ADirector · 68 transactions | — | 137.9Kas of Dec 2018 | 145.2K | — | 20.0K |
| Resch Martin H.President & CEO · 30 transactions | — | 50.9K | 60.7K | 6.4K | — |
| Appelbaum P StephenCFO · 67 transactions | — | 50.8Kas of Jan 2021 | 76.2K | — | — |
| Pickering John FCOO Transportation · 61 transactions | — | 44.8K†as of Jan 2015 | 49.8K | — | 16.1K |
| Langfitt Gary BCOO Utilities · 98 transactions | — | 38.6Kas of Jan 2022 | 81.6K | — | 13.1K |
| Wicks FrankDirector · 58 transactions | — | 34.3K | 29.0K | 700 | — |
| Schilling Randall LDirector · 70 transactions | — | 33.6K | 30.1K | — | — |
| Edwards Benjamin F IVDirector · 35 transactions | — | 29.6K | 19.6K | 5.4K | 5.8K |
| Murray Harry MEVP · 102 transactions | — | 29.1Kas of Jan 2014 | 68.4K | — | 38.5K |
| Ebel Robert ADirector · 20 transactions | — | 27.0K | 19.8K | 2.0K | — |
| Lindemann James JDirector · 71 transactions | — | 25.5K | 28.8K | — | — |
| Rupp Joseph DDirector · 50 transactions | — | 24.0K | 23.2K | — | — |
| Campbell MarkPresident, Transportation · 30 transactions | — | 22.2Kas of Jan 2021 | 17.5K | — | — |
| Erdbruegger Dwight DPresident · 27 transactions | — | 21.8K | 30.9K | — | — |
| Cavellier James M JrCIO · 27 transactions | — | 20.1K | 30.5K | — | — |
| Clermont Ralph WDirector · 56 transactions | — | 18.3K | 22.7K | 1.0K | — |
| Normile Michael JamesCFO · 20 transactions | — | 17.8K | 20.6K | 1.0K | — |
| Grace Wayne JDirector · 56 transactions | — | 17.5K†as of Dec 2015 | 6.7K | 8.1K | 9.7K |
| Mathias Robert JPresident, Cass Bank · 58 transactions | — | 16.9Kas of Jan 2019 | 39.9K | 1.0K | 9.9K |
| Schuckman Matthew StevenExecutive Vice President · 15 transactions | — | 13.5K | 16.7K | — | — |
| Brooksher K DaneDirector · 16 transactions | — | 9.6Kas of Apr 2013 | 3.8K | 5.0K | — |
| Chapell Bryan SDirector · 7 transactions | — | 9.1Kas of Apr 2013 | 3.8K | — | 275 |
| Marr Ann WalterDirector · 6 transactions | — | 8.5K | 8.5K | — | — |
| Henry Wendy J.Director · 5 transactions | — | 8.4K | 8.4K | — | — |
| Roth Sally HDirector · 13 transactions | — | 8.4K | 11.4K | — | — |
| Gillis John L JrDirector · 5 transactions | — | 5.7Kas of Apr 2014 | 4.9K | — | — |
| Drabik John JDirector · 1 transaction | — | 1.7K | 1.7K | — | — |
| Witbrodt Kenneth A JRPresident, CCB · 3 transactions | — | 510as of Oct 2006 | 419 | — | 5.0K |