| Ross Michael JayDirector, 10% owner · 14 transactions | — | 5.15M†as of Nov 2017 | — | 500.0K | — |
| Ragan PaulaPresident and CEO, Director · 52 transactions | — | 3.34Mas of Feb 2025 | 4.27M | — | 928.7K |
| Gordon Carl LDirector, 10% owner · 6 transactions | — | 1.37Mas of Nov 2017 | — | 500.0K | — |
| DiBiase MaryChief Operating Officer · 23 transactions | — | 1.14Mas of Feb 2025 | 1.30M | — | 224.3K |
| Arbet-Engels ChristopheChief Medical Officer · 3 transactions | — | 864.2Kas of Feb 2025 | 875.8K | — | 11.6K |
| Mostafa Adam S.Chief Financial Officer · 33 transactions | — | 850.0Kas of Feb 2025 | 1.65M | — | 798.9K |
| Bill & Melinda Gates Foundation10% owner · 1 transaction | — | 722.2Kas of Nov 2017 | — | — | — |
| SV Life Sciences Fund V LP +4 co-filers10% owner · 14 transactions | — | 712.6Kas of Nov 2017 | — | 500.0K | — |
| Isaly Samuel D +2 co-filers10% owner · 6 transactions | — | 600.7Kas of Nov 2017 | — | — | — |
| Flint Jonathan A +5 co-filers10% owner · 24 transactions | — | 597.5K†as of Nov 2017 | — | 500.0K | — |
| McGuire TerranceDirector, 10% owner · 24 transactions | — | 589.1K†as of Nov 2017 | — | 500.0K | — |
| Alphabet Inc. +3 co-filers10% owner · 1 transaction | — | 451.4Kas of Nov 2017 | — | — | — |
| Maris William J +2 co-filers10% owner · 1 transaction | — | 451.4Kas of Nov 2017 | — | — | — |
| Gerngross Tillman U.Director · 2 transactions | — | 392.8Kas of Nov 2017 | — | 200.0K | — |
| Taveras ArthurChief Scientific Officer · 11 transactions | — | 388.0Kas of Oct 2024 | 566.3K | — | 177.4K |
| Craig Adam RExecutive Chairman, Director · 2 transactions | — | 376.1K | 289.9K | 86.2K | — |
| Volpone JohnPresident · 1 transaction | — | 289.9Kas of Aug 2025 | 289.9K | — | — |
| NeoMed Innovation V L.P. +2 co-filers10% owner · 4 transactions | — | 288.6Kas of Nov 2017 | — | 300.0K | — |
| Nessi ClaudioDirector · 4 transactions | — | 288.6Kas of Nov 2017 | — | 300.0K | — |
| Gray MichaelPresident, CEO and CFO, Director · 1 transaction | — | 250.0Kas of Nov 2018 | 250.0K | — | — |
| Alexandria Venture Investments, LLC10% owner · 1 transaction | — | 225.7Kas of Nov 2017 | — | — | — |
| Kirske DavidChief Financial Officer · 2 transactions | — | 176.3K | 193.3K | — | 17.0K |
| Meisner Derek MChief Legal Officer · 14 transactions | — | 145.2Kas of Aug 2022 | 202.7K | — | 57.6K |
| Cadavid DiegoChief Medical Officer · 3 transactions | — | 104.1Kas of Mar 2022 | 105.0K | — | 928 |
| Adams Jan +4 co-filers10% owner · 3 transactions | — | 103.3Kas of Nov 2017 | — | 20.0K | — |
| Aliski WilliamDirector · 3 transactions | — | 96.7Kas of Jun 2024 | 96.7K | — | — |
| Lawton Alison FrancesDirector · 3 transactions | — | 96.7Kas of Jun 2024 | 96.7K | — | — |
| Skerlj RenatoChief Scientific Officer · 3 transactions | — | 42.1Kas of Sep 2020 | 17.5K | — | 5.8K |
| Anna-Maria & Stephen Kellen Foundation, Inc.10% owner · 2 transactions | — | 25.8Kas of Nov 2017 | — | — | — |
| Baldry MarkChief Commercial Officer · 10 transactions | — | 25.3Kas of May 2025 | 745.7K | 35.0K | 50.5K |
| Stewart MurrayDirector · 5 transactions | — | 7.9Kas of Jun 2025 | 323.1K | — | 130.1K |
| Thoren Natasha FayChief Legal Officer · 1 transaction | — | 7.0Kas of Jun 2025 | 3.3K | — | — |
| Woods KeithDirector · 3 transactions | — | 6.0Kas of Jun 2025 | 136.5K | — | — |
| Wyzga Michael SDirector · 5 transactions | — | 5.6Kas of Jun 2025 | 98.2K | 25.0K | — |
| Bridger GaryDirector · 4 transactions | — | 4.7Kas of Jun 2025 | 98.2K | — | — |
| McGirr David W JDirector · 4 transactions | — | 4.7Kas of Jun 2025 | 98.2K | — | — |
| de Craecker FrancoiseDirector · 4 transactions | — | 4.7Kas of Jun 2025 | 98.2K | — | — |