| Incyte Corp10% owner · 6 transactions | — | 16.97Mas of Jun 2020 | — | 10.00M | 791.0K |
| QVT Associates GP LLC +1 co-filer10% owner · 14 transactions | — | 9.24Mas of Jan 2015 | — | — | 2.34M |
| Malik ShahzadDirector · 4 transactions | — | 1.59M†as of May 2015 | — | — | 1.11M |
| Chadarevian Gamil DeDirector · 1 transaction | — | 1.57M†as of Mar 2006 | 51.6K | — | — |
| Armen Garo HSee Remarks, Director · 267 transactions | — | 426.5K† | 3.16M | 5.21M | 527.0K |
| Duncan AlexChief Technology Officer · 2 transactions | — | 165.0Kas of Jun 2018 | 13.4K | — | 6.5K |
| Hatsopoulos JohnDirector · 3 transactions | — | 130.0K†as of Feb 2009 | — | 30.0K | — |
| Wiinberg UlfDirector · 5 transactions | — | 124.1Kas of Nov 2023 | 53.1K | 55.0K | — |
| Hirsch Susan BDirector · 11 transactions | — | 118.7Kas of Nov 2023 | 53.0K | — | — |
| Sharp ShaliniDirector · 48 transactions | — | 104.3Kas of Sep 2015 | 472.2K | 10.0K | 127.5K |
| Valentine KarenChief Legal Officer · 53 transactions | — | 101.5Kas of Dec 2017 | 385.0K | — | 179.9K |
| Corvese BrianDirector · 3 transactions | — | 92.1Kas of Jun 2021 | 64.8K | — | — |
| Jeynes-Ellis Allison MDirector · 3 transactions | — | 66.2Kas of Jun 2021 | 66.2K | — | — |
| Baysal OzerChief Commercial Officer · 11 transactions | — | 58.8Kas of Dec 2017 | 64.2K | 2.3K | 3.7K |
| Wentworth KerryVP, Clinical, Reg & Qual · 51 transactions | — | 57.4Kas of Feb 2014 | 455.8K | — | 201.2K |
| O'Day Steven JChief Medical Officer · 5 transactions | — | 57.1Kas of Jun 2025 | 354.6K | — | 38.7K |
| Wright TimothyDirector · 5 transactions | — | 55.4Kas of Nov 2023 | 53.1K | 10.0K | — |
| Harrison Thomas LDirector · 5 transactions | — | 39.0K | 39.0K | — | — |
| Ballantyne Charles EvanChief Financial Officer · 3 transactions | — | 24.8Kas of Apr 2016 | 21.9K | 10.0K | — |
| Klaskin Christine MPFO & PAO · 61 transactions | — | 23.5Kas of Jun 2025 | 408.8K | — | 146.2K |
| Stein Robert BenjaminPresident R&D · 2 transactions | — | 21.0Kas of Apr 2016 | 33.4K | — | — |
| Margaret EisenDirector · 1 transaction | — | 20.0Kas of May 2008 | — | 15.0K | — |
| Buell JenniferDirector · 15 transactions | — | 19.7Kas of May 2025 | 112.8K | — | 3.5K |
| Levitsky HyamDirector · 1 transaction | — | 15.4Kas of Feb 2009 | 15.4K | — | — |
| Rothwell Timothy GDirector · 4 transactions | — | 7.4Kas of Oct 2011 | — | — | — |
| Srivastava PramodDirector · 2 transactions | — | 1.6Kas of Feb 2007 | 51.6K | — | 50.0K |
| Afeyan NoubarDirector · 1 transaction | — | 0as of Dec 2006 | — | — | 5.0K |
| Atlee Frank V IIIDirector · 1 transaction | — | 0as of Nov 2006 | — | — | 4.5K |