| Irrevocable Larson Family Investment Trust10% owner · 30 transactions | — | 7.01M†as of Apr 2025 | — | 87.5K | — |
| Curfman Matthew J. +7 co-filersSee Footnotes 1 and 2 · 1 transaction | — | 6.08M†as of Oct 2018 | — | 5.54M | — |
| Curfman Matthew J. +8 co-filersSee Footnotes 1 and 2, See Footnotes 1, 2 and 3 · 43 transactions | — | 5.58M†as of Dec 2020 | — | 211.2K | 842.5K |
| Hagelstein David A10% owner · 54 transactions | — | 3.62M†as of Jan 2013 | — | 220.7K | 99.6K |
| Chioini Robert LChairman, President and CEO, Director · 54 transactions | — | 2.55Mas of Dec 2017 | 3.13M | 10.0K | 186.8K |
| Curfman Matthew J. +6 co-filersSee Footnote 1 · 15 transactions | — | 1.06M†as of Jul 2018 | — | 50.4K | 36 |
| Alexander Coleman Ravich 1991 Irrevocable Trust +4 co-filersSee Footnote 1 · 2 transactions | — | 703.9K†as of May 2017 | — | — | — |
| Klema Thomas EVice President, CFO · 31 transactions | — | 671.5Kas of Dec 2017 | 1.30M | — | 15.0K |
| Gupta AjaySr. VP & Chief Scientific Off. · 19 transactions | — | 574.7Kas of Apr 2020 | 738.5K | 5.0K | — |
| Pratt Raymond DennisVP of Drug Development · 12 transactions | — | 353.4Kas of Apr 2020 | 498.5K | 5.0K | — |
| Paul Stuart MChief Executive Officer, Director · 4 transactions | — | 330.1Kas of Sep 2019 | 388.1K | 10.0K | — |
| Strobeck MarkPresident and CEO, Director · 11 transactions | — | 323.5K | 155.5K | — | 25.1K |
| Ravich Mark HDirector · 20 transactions | — | 292.5K†as of May 2025 | 236.4K | — | 30.0K |
| Bagley Patrick JDirector · 5 transactions | — | 228.5K†as of Dec 2017 | 99.8K | — | — |
| Smith Angus W.Chief Financial Officer · 3 transactions | — | 168.5Kas of Nov 2019 | 166.7K | 10.0K | — |
| Timmins Megan C.See Remarks · 6 transactions | — | 162.4K | 78.5K | — | — |
| Curfman Matthew J. +2 co-filersSee Footnotes 1 and 2, See Footnotes 1, 2 and 3 · 1 transaction | — | 161.3Kas of Jul 2019 | — | — | 179 |
| Radie Robert SDirector · 7 transactions | — | 143.5Kas of May 2025 | 220.5K | — | — |
| Nissenson AllenDirector · 7 transactions | — | 142.6Kas of May 2025 | 210.3K | — | — |
| Smiley Andrea HeslinDirector · 6 transactions | — | 142.1Kas of May 2025 | 204.4K | — | — |
| Cooper John GDirector · 8 transactions | — | 140.4K | 241.7K | — | 5.1K |
| McLaughlin John PeterDirector · 4 transactions | — | 137.0Kas of Jun 2021 | 137.0K | — | — |
| Hunter HeatherChief Operating Officer · 3 transactions | — | 130.1K | — | — | 5.7K |
| Chole TimothySVP and CCO · 8 transactions | — | 122.9K | — | — | 10.6K |
| Neri JesseSVP and CFO · 7 transactions | — | 122.4K | 33.3K | — | 3.5K |
| Lau JoanDirector · 3 transactions | — | 113.1Kas of May 2025 | 111.1K | — | — |
| Boyd Ronald DDirector · 44 transactions | — | 67.3Kas of Dec 2017 | 137.3K | — | 87.5K |
| Smith Robin LDirector · 2 transactions | — | 31.4Kas of Jun 2019 | 31.4K | — | — |
| McGarry Paul ESVP, Finance and CAO · 1 transaction | — | 28.5Kas of Mar 2023 | 28.5K | — | — |
| Wolin BenjaminDirector · 1 transaction | — | 27.7Kas of Jun 2019 | 27.7K | — | — |
| Hoffman Marc LChief Medical Officer · 1 transaction | — | 25.7Kas of Mar 2023 | 25.7K | — | — |
| Dawson Joseph HDirector · 1 transaction | — | 25.0K | 25.0K | — | — |
| Colleran Lisa NDirector · 1 transaction | — | 18.7Kas of Jun 2019 | 18.7K | — | — |
| Holt Kenneth LDirector · 106 transactions | — | 16.7Kas of Mar 2017 | 213.0K | — | 164.0K |
| Kull DavidPrincipal Accounting Officer · 3 transactions | — | 13.3Kas of Apr 2019 | 15.0K | — | — |
| Ellison Russell HSee Remarks, Director · 2 transactions | — | 12.1Kas of May 2020 | 10.1K | 2.0K | — |