Denali Therapeutics Inc.
A biotech company building medicines that can actually reach the brain to fight diseases like Alzheimer's and Parkinson's. Its signature "Transport Vehicle" technology rides drugs across the blood-brain barrier, the natural shield that keeps most treatments out. Three former Genentech scientists founded Denali in 2015, naming it after North America's tallest peak—the Athabascan word for "the high one"—to signal their ambition to conquer the hardest medical challenges.