Trevi Therapeutics, Inc.
A clinical-stage biopharmaceutical company developing Haduvio, an oral extended-release form of nalbuphine that acts on opioid receptors in the cough reflex arc to treat chronic cough. Its lead program targets chronic cough tied to idiopathic pulmonary fibrosis, with additional programs for other interstitial lung diseases and refractory chronic cough. The company has kept worldwide commercial rights to Haduvio.
Estimated from filings — the split-adjusted price range over the quarters each manager built the position. A range, not a fill price; 13F reports a quarter-end snapshot, not a trade date.