N72482AA5

A. [Reserved] B. Capitalization and Indebtedness Not applicable. C. Reasons for the Offer and Use of Proceeds Not applicable. D. Risk Factors MR Risk Factors 27

A. History and Development of the Company MR Business and Operating Environment 6 B. Business Overview MR Conflict Minerals 6 MR Strategy, Business Model and Value Chain 7 APP Government Regulations 203 C. Organizational Structure MR Company Overview 6 EX List of Subsidiaries 225 D. Property, Plants and Equipment MR Description of Property 22

A. Operating Results MR Operating Results 43 B. Liquidity and Capital Resources MR Liquidity and Capital Resources 48 C. Research and Development, Patents and Licenses, etc. MR Research and Development 19 MR Intellectual Property, Proprietary Rights and Licenses 20 QIAGEN N.V. | Financial Report 2025 Management Report Corporate Governance Financial Statements Appendices Page 222 Reference Table Form 20-F Item Form 20-F Caption Section Location in this Document Page MR Research and Development 46 Item 5. D. Trend Information MR Operating Results 43 E. Critical Accounting Estimates MR Critical Accounting Estimates 53