XGN

Exagen Inc.

A medical diagnostics company, Exagen makes blood tests that help rheumatologists tell apart autoimmune conditions like lupus and rheumatoid arthritis. Its flagship product, AVISE CTD, is processed in a single lab in Vista, California, with results typically ready in about five business days. Founded in 2002, the company grows its line of AVISE-branded tests, and the "CTD" in its flagship test's name stands for connective tissue disease—the family of illnesses it helps doctors sort out.

There have been no material changes to the risk factors disclosed in Part I, Item 1A, "Risk Factors" of our 2025 Annual Report. 36